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2019 International Conference on Aging Biology was successfully held in Beijing

2019 International Conference on Aging Biology was successfully held in Beijing

The International Conference on Aging Biology (ICAB 2019), sponsored by Chinese Society for Aging Cell Research, CSCB and presented by the National Clinical Research Center for Geriatric Disorders (Xuanwu Hospital of Capital Medical University), successfully concluded in Beijing International Convention Center on April 20. Top scientists in the field of aging research at home and abroad gathered together to share such an academic feast. The conference attracted about 500 registered participants and presented more than 40 academic reports. The participants were fascinated by the brilliant reports and they actively interacted and exchanged with academic sparks. The scene was very warm and lively.

The conference was chaired by Prof. Guanghui Liu, president of the Senile Cell Biology Branch of the Chinese Society of Cell Biology and researcher of the Institute of Biophysics, Chinese Academy of Sciences (CAS). Prof. Gang Pei, Academician of CAS and honorary president of the conference, and the presents of the conference including Professor Juan Carlos Izpisua Belmonte (USA), Professor Piu Chan, Professor Jingdong Han, Professor Guanghui Liu and Professor Meng Wang (USA) delivered welcoming speeches respectively, and wished the conference a complete success. The opening ceremony was attended by Prof. Tanjun Tong, Academician of CAS and the honorary president of the conference, as well as outstanding scientists and delegates from seven countries and regions, including China, the United States, Spain, Japan, Singapore, Russia and South Korea, in the field of aging research. Centred on the theme of "mechanism and intervention of aging", participants and scholars had heated discussions and exchanged opinions on important scientific topics including "aging mechanism", "aging and regeneration", "metabolism and aging", "genetic and epigenetic regulation of aging", "biomarkers of aging" and "intervention of aging and aging-related diseases".

After the opening ceremony, Prof. Gang Pei's excellent report entitled "Aging: an appealing part of our life" opened the first academic exchange activity of this conference. Prof. Gang Pei made an in-depth analysis of the current research situation and future development prospects in the field of aging, and outlined the key scientific issues and future bottleneck.

Next, more than 40 special reports were presented on "the application of new technologies in aging research", "genomic instability and telomere attrition", "stress, metabolism and homeostasis maintenance", "stem cells, aging and regeneration", "telomere shortening and genomic instability" and "clinical application of aging intervention". The speakers shared the latest research results of their respective teams. They exchanged and interacted with each other both on and off the stage, which manifested the infinite vitality of the research field of aging.

In "The application of new technologies in aging research" session, the invited speakers-Professor Juan Carlos Izpisua Belmonte of the Salk Institute of the United States, Professor Guan-Hui Liu Researcher of Institute of Biophysics, Chinese Academy of Sciences, Professor John m. Sedivy of Brown University, United States, Professor Jing-Dong Jackie Han of Peking University and Professor Wei Xiong of China University of Science and Technology presented their latest work progress, including the applicatoin of a series of new technologies, such as stem cell in vivo reprogramming techniques, gene editing techniques, genome-wide screening techniques, genomic and epigenetic sequencing and system biological analysis, single-cell transcriptomic and mass spectrometry sequencing technology, into the important researches on senescence. Dr. Wang Zhe, editor of Nature Cell Biology, brought a report on "How to efficiently publish high-level articles in the Nature Series magazine."

In "Telomere attrition and genomic instability I" session, Prof. Jan Vijg from Albert Einstein Medical School of the United States, Prof. Zhongjun Zhou of the University of Hong Kong, Professor Junping Liu of Hangzhou Normal University, Professor Yousin Suh of Albert Einstein Medical School of the United States, Professor Zhao Yong of Sun Yat-sen University, Professor Zhang of Jinan University shared their latest works in the area of genomic stability, telomere maintenance, etc., explored the important relationships between genomic instability and aging in single-cell levels and individual levels, and revealed the interaction between genomic stability and stress and mitochondrial function.

In "Stem cell, aging, and rejuvenation" session, Professor Meng Wang from Baylor Medical College, Professor Alexey Moskalev of the Russian Academy of Sciences, Professor Ye Tian of the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, Professor Xiaoli Tian of Nanchang University, Academician Xiaodong Wang of the Beijing Institute of Life Sciences made special reports on the frontier progresses in related fields respectively. Their work revealed important links between lysosome related metabolic pathways, endoplasmic reticulum/mitochondrial foldable protein reactions, cell necrosis and other important cellular biological processes and tissue specific senescence or individual aging, as well as the relationship between genomic and epigenetic stability and homeostasis maintenance under stress responses.

In "Stem cell, aging, and rejuvenation" session, Professor Thomas A. Rando of Stanford University, fellow of the American Academy of Medicine, Professor Ping Hu researcher of the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences, Professor Purificación Muñoz-Cánoves of Pompeu Fabra University, Spain, Professor Jing Qu ofusing researcher of the Institute of zoology of the Chinese Academy of Sciences and Professor Weiqi Zhang of the Beijing Institute of Genomics of the Chinese Academy of Sciences, respectively, demonstrated the latest research results, and studied the mechanism of skeletal muscle, osteoarthritis and vascular senescence through many approaches, such as gene editing technology, animal model and single cell sequencing technology.

In "Telomere attrition and genomic instability II" session, Professor Eiji Hara from Osaka University in Japan, Professor Ming Lei of Shanghai Jiaotong University, Professor Zhou Songyang of Sun Yat-sen University, Professor Lin Liu of Nankai University and Professor Zhiyong Mao of Tongji University reported on the research progresses of multi-model and multi-system in the field of aging. The relationships between chronic inflammatory response, genomic instability, telomere attrition and senescence were discussed, and the important molecular mechanisms of senescence were revealed.

In "stress, metabolism, and homeostasis matainance" session, Prof. Quan Chen from Nankai University, Prof. Chang Chen from Institute of Biophysics, CAS, Prof. Ying Liu from Peking University, Prof. Moshi Song from the Institute of Zoo, CAS, Prof. Jing Ye from Shanghai Jiaotong University, Prof. Yingli Sun from Beijing Institute of Genomics, CAS, and Prof. Zimei Wang from Shenzhen University illustrated the effects of important biological processes such as mitophagy, oxidative stress and ER stress on multiple aging organs, and discussed their effects and mechanisms on genomic stability at the cellular and individual levels.

In "Clinical Application and Aging Interventions" session, Prof. Brian Kennedy from National University of Singapore, Prof. James L. Kirkland from Mayo Clinic in United States, Prof. Piu Chan from the Xuanwu Hospital, Capital Medical University, Prof. Yu Sun from Shanghai Institute of Biological Sciences, CAS, Prof. Jie Wu from Barrow Neurological Institute, St. Joseph’s Hospital and Medical Center in United States, and Prof. Lina Ma from Xuanwu Hospital, Capital Medical University gave excellent reports on aging, chronic diseases and senolytic drugs, and discussed the mecahnisms, aging-protective effects and future clinical translation of dietary restrictions, exercise and drugs.

To encourage more young researchers to actively participate in the academic communication on geriatric and translational medicine, and to share new concepts, technologies, and methods, the International Conference on Aging Biology has established the Excellent Poster Award. From more than 100 abstract submissions received, 30 papers were selected for poster presentation, and after the anoumous voting by acedamic committee and attendee, 12 excellent posters were selected and rewarded.

Subsequently, Prof. Piu Chan, from the Chinese Society for Aging Cell Research, CSCB and the National Clinical Research Center for Geriatric Disorders (Xuanwu Hospital of Capital Medical University), announced that the 2019 International Conference on Aging Biology was successfully held! And Prof. Piu Chan gave deep gratitude to all the attendee, the speakers, the participants and the staff.

This conference gathered the world’s top researchers on aging and regenerative medicine at home and abroad, built a platform for academic exchanges, promoted multidisciplinary cooperation, and pushed forward frontiers of aging research. While completing the establishment of the social security system for the elderly, it is of great scientific and social significance to understand the biological processes of aging, to explore the mysteries of health and longevity, to improve the elderly’s life quality, and to prevent and intervene aging associated diseases at early stage.