2022年全国学术大会 · 厦门





姚雪彪 教授,中国科技大学
YAO Xuebiao, University of Science and Technology of China

毕国强 教授,中国科学院深圳先进技术研究院
BI Guoqiang, Shenzhen Institutes of Advanced Technology,CAS


Global Cell Biology and Synergism:Cell Plasticity and Fine Cyto-architecture Visualization of specific molecules and their interactions in real space and time is essential to delineate how cellular plasticity and dynamics are achieved as perturbation of cellular plasticity and dynamics is detrimental to health. Molecular and cell biologists have traditionally delineated cellular complexity using a reductionist approach by studying molecular components individually. Emerging correlative light and electron microscopic analyses provide a unique approach to elucidate cellular architecture and machinery dynamics at nanometer scale at millisecond resolution. This session provides a unique forum to feature speakers from ASCB│CSCB│EMBO to address how fine cyto-architectures orchestrate cell plasticity in diversified systems.

  • Xuebiao Yao Professor, University of Science and Technology of China
    报告题目:Fine structure and functional adaptations of the kinetochore during mitosis
  • BI Guoqiang Professor, Shenzhen Institutes of Advanced Technology,CAS
    报告题目: Molecular organization in neuronal synapses
  • Jaesung Woo Associate professor, Dept . of Life Sciences, Korea University
    报告题目:Structural insights into the gating mechanism of human Cx43/GJA1 gap junction channel
  • Peijun Zhang Professor, Oxford University
    报告题目:Correlative and multi-scale imaging of virus infection in cells
  • Kai Jiang Professor, Wuhan University
    报告题目:Reconstitution and mechanistic dissection of the human microtubule branching machinery
  • Guangshuo Ou Professor, Tsinghua University
    报告题目:In Situ Structure of Intestinal Apical Surface Reveals Nanobristles on Microvilli
  • Marina Mapelli Professor, European Institute of Oncology
    报告题目:Molecular crosstalk between orientation and fate determination in epithelial cell divisions
  • Chuanmao Zhang Professor ,Peking University
    报告题目:Phase separation in mitotic spindle assembly, structural dynamics and function

刘明耀 教授,华东师范大学 
LIU Mingyao, East China Normal University  

王平 教授,同济大学 
WANG Ping,Tongji University 


Aberrant cell signaling transduction is closely related to tumor initiation and progression. Tumor cell fate determination is in turn tightly controlled by cell signaling transduction and tumor microenvironment. Exploration and dissection of signaling pathways involved in tumor growth, metastasis, cell fate determination or microenvironment regulation using new technologies and new models will largely promote the development of tumor precision medicine. In this session, we will invite experts (both basic and clinical) to share their achievements in the field of tumor cell regulation and targeted therapy.

  • 刘明耀 教授,华东师范大学生命医学研究所
  • 康铁邦 研究员,中山大学肿瘤防治中心
  • 刘强 教授,大连医科大学
  • 江鹏 教授,清华大学
    报告题目:Role of the urea cycle in tumour growth and inflammatory responses
  • 张弩 教授,中山大学附属第一医院
    报告题目:环状MET RNA编码的新蛋白作为胶质母细胞瘤的诊疗靶点
  • 王皞鹏 教授,上海科技大学
  • 王平 教授,同济大学
    报告题目:Methionine restriction promotes cGAS activation and chromatin untethering through demethylation
  • 刘芝华 教授,中国医学科学院肿瘤医院
    报告题目:Anti-PD-L1 免疫治疗联合化疗在三阴性乳腺癌中的作用机制研究
  • 尤涵 教授,厦门大学生命科学学院
    报告题目:The INs and OUTs of METTL3
  • 王桂华 教授,华中科技大学同济医学院附属同济医院
  • 刘文 教授,厦门大学药学院
  • 周文 研究员,中南大学肿瘤研究所
  • 高栋 研究员,中国科学院分子细胞科学卓越创新中心

贾大 教授,四川大学 
JIA Da, Sichuan University 

宋质银 教授,武汉大学 
SONG Zhiyin, Wuhan University 


An organelle is a specialized subunit, in a cell, that has a specific function. Although each organelle has distinctive functions, they often cooperate to function in diverse biological processes. In this session, we aim to recruit established investigators and rising stars to discuss recent breakthroughs in the field including, but not limited to, new organelles, organelle- organelle interaction, mitochondria stress, autophagy, membrane fusion and fission, membrane trafficking, and new techniques in studying organelles.

  • 陈佺 教授,南开大学
    报告题目:Molecular regulation of mitophagy and mitochondrial homeostasis and their contribution to aging associated diseases
  • 史岸冰 教授,华中科技大学
    报告题目:RTKN-1/Rhotekin shields endosome-associated F-actin from disassembly to ensure endocytic recycling
  • 胡俊杰 研究员,中国科学院生物物理研究所
  • 刘兴国 研究员,中国科学院广州生物医药与健康研究院
    报告题目:Mitolysosome exocytosis, a novel mitochondrial quality control in parkinsonism-like symptoms
  • 田烨 研究员,中国科学院遗传与发育生物学研究所
    报告题目:Mitochondrial surveillance pathway and aging
  • 宋质银 教授,武汉大学
    报告题目:The fate of damaged mtDNA under oxidative stress
  • 贾顺姬 研究员,清华大学
    报告题目:A Golgi-derived vesicle potentiates PI4P to PI3P conversion for endosome fission
  • 李巍 教授,首都医科大学儿研所
  • 葛亮 研究员,清华大学
    报告题目:Autophagy regulation in the state of cancer pathogenesis
  • 杨崇林 教授,云南大学
    报告题目:Metabolic damage of mitochondria
  • 徐素宏 研究员,浙江大学
    报告题目:Wound response and repair in C. elegans epidermal membrane
  • 贾大 教授,四川大学
    报告题目:iCAL: 自噬和肿瘤研究的新工具

杨晓 研究员,国家蛋白质科学中心(北京) YANG Xiao, National Center for Protein Sciences (Beijing)

周斌 研究员,中国科学院分子细胞科学卓越创新中心 
ZHOU Bin, Center for Excellence in Molecular Cell Sciences, CAS 


Organ development and tissue homeostasis are tightly orchestrated by a complex of cellular and molecular programs. Aberrant cellular and molecular events may lead to multiple pathological processes, which are associated with diseases. This session would focus on the cellular and molecular mechanism underlying the pathophysiological process in normal and disease conditions. Mechanistic understanding of these biological process would provide new insights on organ development, tissue homeostasis, and diseases.

  • 季红斌 研究员,中国科学院分子细胞科学卓越创新中心
    报告题目: 肺上皮细胞与肿瘤发生
  • 杨中州 教授,南京大学医学院
  • 黄勋 研究员,中国科学院遗传与发育生物学研究所
    报告题目:CDP-diacylglycerol synthase in lipid storage and NASH
  • 陈雁 研究员,中国科学院上海营养与健康研究所
    报告题目:A novel nutritional strategy of diabetes intervention as revealed by single cell analysis of pancreatic islets
  • 杨晓 研究员,国家蛋白质科学中心(北京)
    报告题目:Prmt5 and dilated cardiomyopathy
  • 周斌 研究员,中国科学院分子细胞科学卓越创新中心

徐楠杰 研究员,上海交通大学医学院 
XU Nanjie, Shanghai Jiao Tong University School of Medicine 

郭伟翔 研究员 ,中国科学院遗传与发育生物学研究所 
GUO Weixiang, Institute of Genetics and Developmental Biology, CAS 


The neural development is precisely regulated by extrinsic and intrinsic factors; the structure and function of the nervous system involve sophisticated cellular and molecular mechanisms. The purpose of this topic is to exchange new technologies and achievements in cell biology in the field of development and function of the nerve system, and to provide theoretical guidance for a deeper understanding of the mechanisms of neural developmental and functional regulation at the cellular and molecular levels.

  • 罗振革 教授, 上海科技大学
    报告题目:Comparative gene expression profiling reveals intrinsic heterogeneity in axon regeneration
  • 赵春杰 教授, 东南大学
    报告题目:FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons
  • 郭伟翔 研究员, 中国科学院遗传与发育生物学研究所
    报告题目:Metabolic regulation of adult neurogenesis
  • 鲍岚 研究员, 中国科学院分子细胞科学卓越创新中心
    报告题目:The functions and regulatory mechanisms of long intergenic noncoding RNAs in neuronal development
  • 许执恒 研究员, 中国科学院遗传与发育生物学研究所
  • 徐楠杰 教授, 上海交通大学医学院
    报告题目:Neuronal calcium homeostasis and synapse stabilization

张勇 教授,苏州大学 
ZHANG Yong, Soochow University 

秦曦明 副教授,安徽大学 
QIN Ximing, Anhui University 


Biological clock is the timekeeping mechanism that synchronizes selfsustained rhythms in physiology and behavior to the cyclic changes of environmental cues. 
This session will discuss the biological clock and external zeitgebers, pacemaker mechanism, as well as the significance of biological clock for physiology and health.

  • 吴宝剑 教授,广州中医药大学
  • 徐小冬 教授,河南大学
  • 秦曦明 副教授,安徽大学
  • 徐璎 教授,苏州大学
    报告题目:No clock is better than a good clock in response to an acute stress
  • 鞠大鹏 教授, 重庆医科大学附属第二医院
    报告题目:The pancreatic clock is a key determinant of fibrosis progression and exocrine dysfunction
  • 张勇 教授,苏州大学
    报告题目:A conserve role of YIPPEE in regulation of circadian clock

余鹰 教授, 天津医科大学 
YU Ying, Tianjin Medical University 

孙宁 教授/研究员, 复旦大学 
SUN Ning, Fudan University 


Cardiovascular diseases (CVDs) remain to be pandemic over the world and are the main global cause of death. Metabolic disorders are implicated in various CVDs such as heart failure and atherosclerosis. The underlying molecular mechanisms for metabolic disorders in CVDs, and the related potential therapeutic targets and translational applications in clinics need to be further explored. In this section- “Metabolic regulation and CVDs”, novel research findings regarding mechanistic insight in metabolic CVDs, and metabolic interventions for CVD therapy will be discussed.

  • 付毅 教授,北京大学基础医学院
  • 季勇 教授,南京医科大学
  • 陶凌 教授,西京医院
  • 祝之明 教授,重庆大坪医院
  • 余鹰 教授,天津医科大学
    报告题目:CRTH2 与器官纤维化
  • 孙宁 教授,复旦大学

周大旺 教授,厦门大学生命科学学院 
ZHOU Dawang, Xiamen University 

赵斌 教授,浙江大学生命科学研究院 
ZHAO Bin, Zhejiang University 


The Hippo pathway plays key roles in cell proliferation and cell death, self-renewal and differentiation, organ size control and regeneration. Furthermore, its deregulation leads to cancer and other diseases. In recent years, it has attracted broad attention in the fields of cell biology, developmental biology, and cancer biology. Chinese scientists have made critical contributions to the establishment of the Hippo pathway, and continuously impact the field by frontier discoveries. In this session we will discuss recent advances in regulations and functions of the Hippo pathway.

  • 周大旺 教授,厦门大学生命科学学院
    报告题目:Role of glycogen in liver cancer initiation
  • 徐平龙 教授,浙江大学生命科学研究院
    报告题目:Measured Hippo signaling in organ regeneration and antitumor immunity
  • 张雷 研究员,中国科学院分子细胞科学卓越创新中心
    报告题目:Feedback regulation of Hippo Signaling in Organ Development, Regeneration, and Tumorigenesis
  • 孙书国 教授,华中科技大学
    报告题目:YAP Phase separation and transcriptional activation in cancer
  • 袁增强 研究员, 北京基础医学研究院
  • 林爱福 研究员,浙江大学
    报告题目:LncRNA: a new regulator in Hippo signaling

李国红 研究员,中科院生物物理所
 LI Guohong, Institute of Biophysics, CAS 

沈晓骅 教授,清华大学医学院 
SHEN Xiaohua, Tsinghua University School of Medicine 


Transcription, RNA processing and genome organization are intrinsically coupled and play important roles in the operation and homeostasis of the nucleus during development and differentiation. This session will focus on the cutting-edge advances and crosstalk between RNA processing, transcription, and the higher-order chromatin structure in the regulation of stem cell fate, and how their dysregulation leads to human disease.

  • 文波 研究员,复旦大学
    报告题目:Roles of nuclear matrix and repeat element-derived RNAs in nuclear organization.
  • 柳欣 研究员,中国科学院分子细胞科学卓越创新中心
    报告题目:Deciphering non-coding regulatory genome in development and diseases
  • 尹亚飞 研究员,浙江大学
    报告题目:U1 snRNP: functions and regulation
  • 李国红 研究员,中国科学院生物物理研究所
    报告题目:Structural basis of genome folding and its functions in gene regulation and epigenetic inheritance
  • 沈晓骅 教授,清华大学医学院
    报告题目:RNA homeostasis, transcription and nuclear organization
  • 周琦 教授,浙江大学生命科学研究院
    报告题目:Evolution of chromosome numbers and nuclear architecture of amniotes

何志颖 教授,同济大学附属东方医院 
HE Zhiying, Shanghai East Hospital of Tongji University 

黄鹏羽 教授,中国医学科学院生物医学工程研究所 
HUANG Pengyu, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences 


The liver plays a central role in the metabolism of nutrients, detoxification, storage of glycogen, and syntheses of secretory proteins. The liver injury could be induced by the virus infection, drugs, autoimmune disease, metabolic disorder, etc. Continuous exposure to the pathogenic factors could result in liver failure and liver cancer. The emerging regenerative medicine strategies, such as gene therapy, cell therapy, and tissue engineering, provide cutting-edge directions for treating liver diseases. This session will focus on the regulatory mechanisms, medical technologies, clinical and translational medicines of liver regeneration and discuss the advanced development of liver regeneration research from basic to clinical research.

  • 彭金荣 教授, 浙江大学动物科学学院
  • 徐成冉 研究员, 北京大学
  • 董磊 教授,南京大学
  • 黄鹏羽 研究员, 中国医学科学院生物医学工程研究所
    报告题目:CPA-seq reveals sRNome remodeling during hepatic reprogramming
  • 廉哲雄 教授,华南理工大学生命科学研究院
    报告题目:Nanoparticle mediated therapeutic modulation of biliary inflammation via alteration of macrophage autophagy in murine primary biliary cholangitis
  • 胡文祥 研究员,广州实验室基础研究部
  • 胡军浩 研究员,中国科学院生物与化学交叉研究中心
    报告题目: The hepatic stellate cell activation roadmap during liver fibrosis and its applicaton
  • 覃文新 研究员,上海市肿瘤研究所
    报告题目: 肝癌精准治疗的基础研究与转化应用
  • 何志颖 教授,同济大学附属东方医院
    报告题目: 肝细胞衰老与肝癌发生
  • 鄢和新 教授,上海交通大学医学院附属仁济医院
    报告题目: Phenotypic and functional differences of in vitro expanded liver progenitor-like cells from distinctive sources
  • 苏 娟 研究员,上海干细胞转化医学工程技术研究中心
    报告题目: 人羊膜上皮干细胞特性及其临床研究进展

李劲松 院士、研究员,中科院分子细胞科学卓越创新中心(生化与细胞所) 
LI Jinsong, Center for Excellence in Molecular Cell Science, CAS 

万国强 副教授,南京大学模式动物研究所 
WAN Guoqiang, Model Animal Research Center, Nanjing University 


Haploid embryonic stem cells and stem cell-derived organoids provide unprecedented cellular models for research in life sciences. Haploid embryonic stem cells not only allow high throughput genetic screening in live mice, but also facilitate robust genetic modifications by “pseudo-fertilization” for studies in embryonic development and cell fate determination. Organoids are derived from stem cells and cultured as 3D mini-organs. Over the years, organoid technology has greatly promoted research into human genome functions, biobanking, disease modeling and pathological studies, drug screening and regenerative medicine. This forum will focus on the development and applications of these new cell models in unraveling the molecular and cellular mechanisms in genetic, developmental and regenerative biology.

  • 李劲松 院士、研究员,中国科学院分子细胞科学卓越创新中心
  • 万国强 副教授,南京大学模式动物研究所
    报告题目:Applications of cochlear organoids for hair cell development and regeneration 
  • 帅领 教授,南开大学
    报告题目:Genome-scale Screening in a Rat Haploid System Identifies Thop1 as a Modulator of Pluripotency Exit
  • 李伟 教授,中国科学院动物研究所
    报告题目:Balancing embryonic development through"imbalance"
  • 林鑫华 教授,复旦大学
    报告题目:The application of organoid technology in organ development and homeostasis
  • 刘妍 教授,南京医科大学
  • 谭韬 教授, 昆明理工大学灵长类转化医学研究院

韩俊海 教授 东南大学 
HAN Junhai, Southeast University 

仇子龙 研究员,中国科学院脑科学与智能技术卓越创新中心  
QIU Zilong, Center for Excellence in Brain Science and Intelligent Technology, CAS  


Signal transduction is a fundamental process in nervous system and deficits in signal transduction pathways lead to many neural diseases. This forum invites some well-established scientists to share their research progresses in this field.

  • 吴海涛 研究员, 军事医学研究院
    报告题目:Deciphering the mechanisms underlying cognitive impairment in autism spectrum disorders
  • 韩俊海 教授, 东南大学
    报告题目:PQBP1 regulates brain development
  • 朱铃强 教授, 华中科技大学同济医学院基础医学院
    报告题目:Tau epigenetically remodels the neuron-glial crosstalk in Alzheimer’s disease
  • 杨竞 教授, 北京大学
    报告题目:SARM1 as a neuro-immune signaling nexus
  • 曲宜波 研究员, 暨南大学
    报告题目:Celsr2: wiring, regrowth and plasticity
  • 仇子龙 研究员, 中国科学院脑科学与智能技术卓越创新中心
    报告题目:Decoding genetic basis and neural circuitry for autism spectrum disorders

韩敬东 研究员,北京大学 
HAN Jackie, Peking University 

刘光慧 研究员,中国科学院动物研究所 
LIU Guang-Hui, Institute of Zoology, CAS 


The increasing population aging and the high incidence of aging-related diseases are major social and scientific issues worldwide. The aging of tissues and organs in the whole body and the aging-related decline of tissue regeneration capacity are main factors leading to aging and aging-related diseases. It is of scientific importance to the field of aging and regeneration that we manage to use integrated methods to comprehensively dissect the regulatory pathways underlying aging and regeneration of tissues and organs, to reveal their molecular mechanisms, to discover new molecular targets that can promote tissue and organ regeneration, and to develop efficient and safe aging interventions. This session focuses on the topic of "aging and regeneration", involving studies using different model animals and aging-related disease models via the integrative analyses through single-cell multi-omics, multi-dimensional omics analysis and big data analysis and other cutting-edge technologies to dissect the molecular mechanisms of aging and regeneration and identify potential targets treating aging and aging-related diseases or promoting tissue and organ regeneration, thus providing scientific basis for achieving healthy aging.

  • 韩敬东 教授,北京大学
    报告题目:Heterogeneity of Human Aging
  • 刘光慧 研究员,中国科学院动物研究所
    报告题目:Programming and reprograming of aging
  • 松阳洲 教授,中山大学
    报告题目:Telomere Regulatory Networks: from protein complexes to nuclear bodies
  • 鞠振宇 研究员,暨南大学
  • 刘强 教授,中国科学技术大学
  • 宋默识 研究员,中国科学院动物研究所
    报告题目:Exhaustion of Mitohormetic Buffering Capacity for Cytosolic Proteotoxic Stress Accelerates Myocardial Degeneration and Aging

宋保亮 院士、教授, 武汉大学 
SONG Bao-Liang, Wuhan University 

陈帅 教授,南京大学 
CHEN Shuai, Nanjing University 


Metabolism of glucose and lipids is a fundamental physiological process for life, not only providing energy for physical activities but also producing building blocks required for biosynthesis. Multiple mechanisms involving regulatory networks are required to maintain metabolic fitness, which can be deteriorated by genetic, dietary or environmental factors. The impairment of metabolic homeostasis may result in various diseases such as metabolic disorders, cardiovascular diseases and cancer. This section will focus on recent processes on the regulation of metabolic homeostasis and the pathological mechanisms in diseases related to metabolic abnormalities, and aim to exchange thoughts and to promote networking among participants.

  • 卜鹏程 研究员,中国科学院生物物理研究所
  • 赵同金 教授,复旦大学代谢与整合生物学研究院
    报告题目:Dynamic palmitoylation regulates fatty acid uptake
  • 陈帅 教授,南京大学
  • 李朝军 教授,南京医科大学
    报告题目:GGPP, an Isoprenoid from the Mevalonate Pathway, Allosterically Activates FBP1 to Coordinate Glucose Metabolism with Cholesterol Biosynthesis
  • 邱义福 研究员,北京大学
    报告题目:Remodeling adipose tissue for metabolic health

赵忠 教授,中国科学技术大学
 ZHAO Zhong, University of Science and Technology of China 

焦雨铃 研究员,中国科学院遗传与发育生物学研究所 
Yuling Jiao, Institute of Genetics and Developmental Biology, CAS 


Plant meristems harbor stem cells, and maintain organogenesis potential in post-embryonic development. Stem cell maintenance and differentiation, and organ initiation and morphogenesis are central to plant developmental biology. This session covers mechanisms underlying plant stem cell homeostasis and organogenesis, with focuses on new advances, new technologies, and interdisciplinary studies.

  • 黎家 教授,兰州大学
    报告题目:Regulation of root apical meristem development by a group of small peptides, RGFs
  • 李传友 研究员,中国科学院遗传与发育生物学研究所
    报告题目:SEUSS integrates transcriptional and epigenetic control of root stem cell organizer specification
  • 焦雨铃 教授,北京大学
  • 赵忠 教授,中国科学技术大学
    报告题目:WUSCHEL triggers innate antiviral immunity in plant stem cells
  • 孙博 教授,南京大学
    报告题目:Robust control of floral meristem determinacy by position-specific multifunctions of KNUCKLES
  • 杨卫兵 研究员,中国科学院分子植物科学卓越创新中心

尹芝南 教授,暨南大学 
YIN Zhinan, Jinan University 

陈兰芬 教授,厦门大学
CHEN Lanfen, Xiamen University 


In response to the external stress and internal homeostasis imbalance, the body adapts to multi-level regulation and changes relying on the crosstalk of the nervous and immune systems. This conference will invite the researchers who interest in the study on the interaction between emotion, behavior, stress, nerve injury and immunology, and carry out in-depth communications on mutual regulation mechanism of nerve and immune system under physiological and pathological conditions. This conference will provide new ideas for the diagnosis and treatment of psychological disorders and immune-related diseases.

  • 尹芝南 教授,暨南大学
    报告题目:gdT and microbiom in social behavior and depression
  • 马瑜婷 研究员,中国医学科学院系统医学研究院
  • 靳津 教授,浙江大学
    报告题目:Metabolic disorders in T cells leads stress-associated diseases
  • 杨辉 研究员,复旦大学
    报告题目:A role of cGAS-STING signaling in controlling neuroinflammation
  • 占成 教授,中国科学技术大学
  • 施福东 教授,天津医科大学总医院
  • 陈兰芬 教授,厦门大学
    报告题目:Mechanical force activates Hippo signaling to regulate host defense immunity
  • 周荣斌 教授,中国科学技术大学
  • 曾文文 特别研究员,清华大学
    报告题目:Connecting the brain and periphery: neural control of lipid metabolism and neuroimmune response
  • 谷岩 研究员,浙江大学
    报告题目:Forgetful little glia: microglia and forgetting
  • 刘强 教授,天津医科大学总医院
    报告题目:The immunology of stroke
  • 彭勃 研究员,复旦大学

黄俊 教授,浙江大学生命科学研究院 
HUANG Jun, Life Sciences Institute, Zhejiang University 

许兴智 教授,深圳大学医学部 
Xingzhi (Xavier) Xu, Shenzhen University School of Medicine 


Chromatin replication involves both DNA replication and chromatin assembly. The current understanding of the mechanism of eukaryotic DNA semi-reserved replication mainly comes from the study of single-celled eukaryotic organisms such as yeast, while the understanding of the mechanism of DNA replication in mammalian cells is still emerging. Emerging evidences indicate that parental histones recycled from disassembled nucleosomes immediately ahead of the fork and newly synthesized naïve histones are mixed in a 1:1 ratio on newly replicated DNA. Deregulation of chromatin replication contributes to the initiation and progression of many human diseases such as cancers, aging and rare genetic disorders. In this session we invite outstanding experts and scholars for exchange and discussion focusing on chromatin replication and human diseases.

  • 许兴智 教授,深圳大学
    报告题目:Ubiquitination of CLASPIN regulates the ATR-CHK1 checkpoint pathway
  • 朱卫国 教授,深圳大学
    报告题目:Epigenetic regulation of replication stress response
  • 黄俊 教授,浙江大学
    报告题目:RNF4 controls the extent of replication fork reversal to preserve genome stability
  • 李磊 教授,浙江大学
    报告题目: DNA crosslinking damage and the molecular pathology of  Fanconi anemia
  • 袁健 教授,同济大学
  • 龙海珍 研究员,中国科学院生物物理研究所
    报告题目:Epigenetic regulation of DNA replication

邹鹏 研究员,北京大学 
ZHOU Peng, Peking University 

刘行 教授, 中国科学技术大学 
LIU Xing, University of Science and Technology of China 


Cells are capable of dynamically and precisely altering their architect and function in response to environmental stimuli and internal clock, in a reversible process called cell plasticity. Through creating chemistry-enabled tools, chemical biology provides unique views into the signal transduction pathways and biological macromolecules that underlie cell plasticity. This session will highlight emerging techniques and new discoveries in the field of cell plasticity, with the aim of understanding the molecular mechanism and achieving spatiotemporal regulation of cell plasticity.

  • 杨财广 研究员,中国科学院上海药物研究所
    报告题目:Aberrant activation of ClpP proteases in bacterial and mammalian cells
  • 伊成器 教授,北京大学生命科学学院
  • 邹鹏 研究员,北京大学化学与分子工程学院
  • 邓贤明 教授,厦门大学
    报告题目:Target identification of bioactive natural product piperazic acid containing pyranylated cyclodepsipeptides
  • 吴乔 教授,厦门大学
    报告题目:Compound PDNPA targets nuclear receptor Nur77 to repress HCC through intercepting ectosomal HK1 release
  • 刘行 教授,中国科学技术大学
    报告题目:Molecular delineation of EB1 code in mitosis

Miguel Esteban 研究员, 中国科学院广州生物医药与健康研究院 
Miguel Esteban, Guangzhou Institutes of Biomedicine and Health, CAS 

刘龙奇 研究员,深圳华大生命科学研究院 
LIU Longqi, BGI-Research 


Spatially resolved transcriptomic technologies are promising tools to study cell fate decisions in a physical microenvironment. This seminar session will focus on cutting-edge approaches, algorithms, and application to answer complex biological questions.

  • Miguel Esteban 研究员,中国科学院广州生物医药与健康研究院
    报告题目:Mammalian biology at tissue scale using Stereo-seq
  • 李澄宇 研究员,中国科学院脑科学与智能技术卓越创新中心
    报告题目:Global Spatial Transcriptome of Macaque Brain at Single-Cell Resolution
  • 费继锋 研究员,广东省人民医院
    报告题目:Using axolotl as a model for dissecting the mechanisms of CNS regeneration
  • 陈洛南 研究员,中国科学院分子细胞科学卓越创新中心
  • 彭广敦 研究员,中国科学院广州生物医药与健康研究院
    报告题目:Molecular architecture and tissue patterning of development and injury by integrative spatial transcriptome
  • 刘龙奇 研究员,深圳华大生命科学研究院
    报告题目:Large-field of view, high-resolution spatially resolved transcriptomics using DNA nanoball patterned arrays

王光辉 教授,苏州大学 
WANG Guanghui, Soochow University 

张维绮 研究员,中国科学院北京基因组研究所(国家生物信息中心) 
ZHANG Weiqi, Beijing Institute of Genomics, China National Center for Bioinformation, CAS   


Brain is an organ that integrates sensory information and controls movement. It is also involved in intellectual functions, such as speech, learning, thought and emotion. Aging of the central nervous system leads to the decline of neuronal function and cognition, which is tightly associated with stroke, neurodegenerative diseases and dementia. Although the brain changes with aging is clear, the mechanism underlying aging process is still largely unknown. Our session focuses on the theme for aging in the central nervous system, exploring the mechanism of brain aging and the strategy of intervention.

  • 申勇 教授,中国科学技术大学
  • 李晓江 教授,暨南大学
  • 许华曦 教授,厦门大学
  • 王思 教授/研究员,首都医科大学宣武医院
    报告题目:Single-Cell Transcriptomic Atlas of Primate Organ Aging
  • 王光辉 教授,苏州大学
  • 张维绮 教授,中国科学院北京基因组研究所(国家生物信息中心)
    报告题目:Single-nucleus profiling identifies microglia subsets exacerbating motor neuron aging in primate spinal cord

周天华 教授,浙江大学 
ZHOU Tianhua, Zhejiang University  

林欣 教授,清华大学 
LIN Xin, Tsinghua University 

恶性肿瘤的遗传性、异质性以及动态演变过程已成为人类在恶性肿瘤治疗上的巨大挑战。以基因组信息为基础,结合蛋白质组、代谢组等相关内环境信息,为病人量身设计出最佳治疗方案,已成为肿瘤治疗的未来趋势所在,也在推动肿瘤精准诊疗的快速发展。基于大数据的精准医学为我们进一步探索肿瘤诊疗策略提供了巨大空间,需要生物学家、生物信息技术学家、医生等多方积极参与, 最终引领肿瘤医学进入一个全新的时代。

The heredity, heterogeneity, and dynamic progression of malignant tumors have been significant challenges for the treatment of malignant tumors. To overcome these challenges, integrating different omics, such as genomics, proteomics, and metabolomics, has been employed to be the best strategy to treat cancer patients. It, therefore, is becoming the trend of cancer treatment and promoting the rapid development of cancer precision medicine. By taking advantage of high throughput data, precision medicine will explore the opportunities to develop an effective cancer diagnosis and treatment strategy. Therefore, more experts in different backgrounds, such as biologists, bioinformatics scientists, and doctors, urgently need to work together to lead cancer research into a new era.

  • 周天华 教授,浙江大学
    报告题目:RNA modifications in gastrointestinal tumors
  • 林欣 教授,清华大学
    报告题目:Developing TCR-based CAR-T cell approach for cancer immunotherapy
  • 潘登 助理教授,清华大学
    报告题目:Systematic identification of tumor intrinsic resistance mechanisms to immune cell-mediated killing
  • 崔儒涛 教授,浙江大学
  • 王秀杰 研究员,中国科学院遗传与发育生物学研究所
  • 杨巍维 研究员,中国科学院分子细胞科学卓越创新中心
    报告题目:Metabolic rewiring in tumor cells
  • 庄诗美 教授,中山大学生命科学学院

钟清 教授,上海交通大学 
ZHONG Qing, Shanghai Jiao Tong University 

莫玮 教授,厦门大学 
MO Wei, Xiamen University 


Cell death is the termination of vital activities. Cell death is crucial for animal development and pathophysiological functions. This session will mainly discuss different types of cell death pathways and their relationship to inflammation and human diseases, as well as underlying molecular mechanisms.

  • 钟清 教授,上海交通大学
  • 莫玮 教授,厦门大学
  • 孙丽明 研究员,中国科学院分子细胞科学卓越创新中心
    报告题目:Necroptosis on the brakes
  • 邵峰 院士、研究员,北京生命科学研究所
    报告题目:Pyroptosis in antibacterial and antitumor immunity
  • 许代超 研究员,中国科学院上海有机化学研究所生物与化学交叉研究中心 
    报告题目:The orchestration of TNF-RSC through SENP1-mediated RIPK1 deSUMOylation determines cell death susceptibility
  • 吕奔 教授,中南大学湘雅医院

王佳伟 研究员, 中国科学院分子植物科学卓越创新中心 
WANG Jia-Wei, Center for Excellence in Molecular Plant Sciences, CAS 

严建兵 教授,华中农业大学 
YAN Jianbing, Huazhong Agricultural University 


Recent technological advances have provided us unprecedented opportunities to analyze plant development and physiology at the single-cell level. High-throughput analyses of the genomes, epigenome and transcriptomes of single cells are providing novel and important insights into diverse processes such as cell differentiation, adaptation, gene-expression dynamics and epigenetic reprogramming. The theme of the session aims to invite young speakers with recent breakthroughs on the topics of plant single-cell omics study and provide a forum for open discussion among scientists working on related topics.

  • 翟继先 研究员,南方科技大学
    报告题目:FlsnRNA-seq: protoplasting-free full-length single-nucleus RNA profiling in plants
  • 钱文峰 研究员,中国科学院遗传与发育生物学研究所
  • 秦源 教授,福建农林大学
  • 王佳伟 研究员,中国科学院分子植物科学卓越创新中心
    报告题目:Single-Cell transcriptome atlas and chromatin accessibility landscape reveal differentiation trajectories in the rice root
  • 王鹏程 研究员,中国科学院分子植物科学卓越创新中心
    报告题目:A cell type-specific multiomics uncovers a guard cell-specific RAF15-SnRK2.6/OST1 kinase cascade
  • 严建兵 教授,华中农业大学

刘艳芬 研究员,上海科技大学 
LIU Yanfen, ShanghaiTech University 

王洪睿 教授,厦门大学 
WANG Hongrui, Xiamen University 

卢克锋 研究员,四川大学
LU Kefeng, Sichuan University 


Cellular protein homeostasis is essential for cell viability and human health. Various diseases are associated with the disturbance of this balance. Autophagy and the ubiquitin-proteasome system play pivotal roles in the breakdown of intracellular unwanted materials and furthermore in the maintenance of protein homeostasis. In this session, our young scientists will share their recent breakthroughs on the topic of protein homeostasis and disease.

  • 邱小波 教授,北京师范大学
  • 冯新华 教授,浙江大学
    报告题目:Insensitivity to TGF-β Antigrowth Signals in Cancer
  • 刘艳芬 研究员,上海科技大学
    报告题目:Linear ubiquitination regulates autophagy initiation and maturation to protect the host against infection
  • 王洪睿 教授,厦门大学
    报告题目:Monomeric EGFR-mediated STAT3 signaling in triple-negative breast cancer
  • 卢克锋 研究员,四川大学



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